Supports the In Vivo team on preclinical projects by providing exceptional quality animal care and technical support services for animal research. Contributes to advancing human health, developing new treatments, and improving exiting treatments for cancer while ensuring safe and human treatment of animals. Works to advance preclinical drug development programs from target identification/validation through IND enabling activities.
The in vivo specialist is responsible for supporting the Senior In vivo Supervisor in the preparation and execution of vivo studies performed at OncoSec Medical.
ESSENTIAL JOB DUTIES/RESPONSIBILITIES:
- Interacts with scientists on a regular basis to understand the needs and goals of the projects and help coordinate logistics of the research
- Tumor measurements by caliper
- Assists with collection of tissue, processing of samples, sample assay and analysis
- Maintains breeding and genotyping of mouse colonies
- Maintains animal census, conducts overall health checks and orders laboratory reagents
- Dosing via SQ/SC, I-TUMOR, IV, IP, IM, and PO routes
SECONDARY DUTIES AND RESPONSIBILITIES
- Electroporation using OncoSec’s proprietary electroporation device.
- Surgical manipulation (minor/major)
- Adoptive transfer of Lymphocytes
- Follows appropriate rules, regulations, and guidelines for animal care and use, combined with chemical and biological safety
- Maintain clear and up-to-date notebook records of research objectives, methods and results
- Participate in R&D group meetings as needed
- Bachelor’s degree in a relevant biological discipline (life sciences or Veterinary Technology, RVT, AHT) or a combination of education, AALAS certification (ALAT, LAT, LATG, CMAR) and applicable work experience or organizational work with 4H, FFA, Grange with successful raising of animals.
- 1+ years of relevant vivarium experience in an academic or pharmaceutical research setting in a combination of the following areas:
- A minimum of six (6) consecutive months of humane handling and manipulating mice or other rodents.
- Must be proficient in handling rodents
- Experience with rodent related techniques such as injections via various routes, blood and animal tissue collection is desirable
- Experience with tumor measurements via caliper desirable
- Knowledge of Standard Operating Procedures for animal facilities and basic requirements for maintaining laboratories animals and performing scientific procedures involving animal testing and data collection
- Ability to work in a team or independently and communicate with management in a demanding scientific environment.
- Ability to keep detailed and accurate computer records and maintain/update data in computer-based applications/databases
- Ability to lift up to 50 lbs. and to wear appropriate personal protection equipment when necessary.
Applies company policies and procedures to analyze situations or data and to resolve a variety of problems. Works on problems of diverse scope following standard practices and procedures to analyze situations or data. Normally receives guidance on day to day work and detailed instructions on new assignments.
While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk or hear in a standard office environment. In a lab setting, occasionally use hands to finger, handle objects, tools, or controls. Employee must occasionally lift and/or move up to 20 pounds.
To apply, please send a copy of your résumé to Tahmeena Nizam